Cialis: Some Interesting Facts

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cialis


With the increasing modern lifestyle, people are falling prey to new ailments without even being aware of it. Erectile dysfunction in men is one such side effect of a modern lifestyle that is getting common day by day. According to a John Hopkins study report, more than 18 million men in the only U.S. have been a victim of erectile dysfunction.

But research and development are taking place at the same rate to counter these statistics. First line treatments like Cialis are becoming more popular day by day. These erectile dysfunction medicines have become the go-to pills for the treatment of Impotence (or erectile dysfunction). Cialis is a popular ED pill that has helped millions of men to overcome this condition of Impotence. Before you buy Cialis, you must get an approval from your doctor. Also, make sure that the pharmacy is a trusted store.

Let us learn about this particular ED pill by going through the fast facts given below.

Facts on Cialis: The Popular ED pill

•    Cialis belongs to a group of medications called PDE5 (phosphodiesterase type 5) inhibitors. It helps inhibit the PDE5 enzyme from causing erectile dysfunction in men.
•    The active ingredient in Cialis is Tadalafil. This is also the generic drug for the treatment of pulmonary arterial hypertension and benign prostatic hyperplasia.
•    Cialis is available in flexible dosing forms. For instance, there is Cialis for a daily dose (Cialis 2.5 mg and 5 mg) and another for occasional dose (Cialis 10 mg and 20 mg).
•    The Cialis 10 mg and 20 mg pills have a longer half-life which can have effects up to 24 or 36 hours. This is why this ED pill is also titled as the Weekend Pill simply because it can last through the weekend.
•    You can take this dose with or without food. There are no strict rules of taking Cialis with food intake. In both cases, the effectiveness of the medication is same.
•    Cialis should not be taken with grapefruit or grapefruit juice as there can be interactions. Users of this ED pill are also advised to avoid alcoholic drinks while taking Cialis as it can reduce the effects of the drug.

How does Cialis work?

cialis


Being a PDE5 inhibitor, Cialis can inhibit the production of an enzyme called PDE5 (phosphodiesterase type 5) which is mostly found in men with erectile dysfunction. This enzyme can break down the chemicals called cGMP (cyclic guanosine monophosphate) essential for relaxing the muscles around the penile blood vessels.

Along with sexual stimulation that releases nitric oxide, there is a conversion of GTP (guanosine triphosphate) molecule to cGMP.  Cialis can stop the PDE5 enzyme from degrading the cGMP chemicals. This allows the relaxation of the muscles around the blood vessels. The blood flows freely to the erectile tissue called corpus cavernosum and an erection is obtained.

How to take Cialis for ED?

The ideally recommended dose is 10 mg for most men. You can increase or decrease the dose depending on your health condition and tolerance. But for this, you must have your doctor’s approval. 

•    You can take Cialis 30 minutes before any physical intercourse. Within 30 minutes of its intake, this pill starts showing its effects.
•    Do not take this medication more than once in a day.
•    You can take it with or without food. There are no hard and fast restrictions.
•    Do not increase or decrease a dose without an approval from the doctor.

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